From: Lynn McIntosh [faiml@uswest.net] Sent: Saturday, October 16, 1999 10:12 AM To: mjanke@miamiferret.org Subject: (Fwd) Adrenal List #40 Forwarded message: From: Self To: @SENDLIST.PML Subject: Adrenal List #40 Reply-to: Lynn McIntosh Date: Wed, 25 Feb 1998 18:54:31 Hi there. To those who I'm sending all the lists. This one is cut off, so I'll have to post a request to the list that someone send me a complete #40. Sorry! Lynn Mc. Adrenal List #40, dated August 24, 1997 1. Lysodren 2. Need to make decision on initial approach w/Seldon (possibly to post) 3. Fwd: Adrenalectomy 4. Thank You (Grimmy) 5. Lysodren 6. For adrenal list - more sneezing problems 1.---------- Forwarded message ---------- Date: Wed, 20 Aug 1997 07:43:24 -0400 From: "Michael F. Janke" Subject: Lysodren > From: Barbara Gustafson > Subject: Tippie: Adrenal list or not (it's up to you) > > So Lynn I do seem to recall that you were asking for some specific > information about dosages etc and I was hoping you could pass what you've > learned on to me. I guess what he does is phone the prescription into a > pharmacist and they make it up. Apparently its in a liquid form, it that > right? I've treated two ferrets with Lysodren and both times it was in liquid form, but everyone else I hear talk about it here and on the FML seem to get it in some sort of pill form that has to be crushed and mixed with something to give it to them. The last time it was in this VERY thick liquid that was sweet as could be and tasted sorta like vanilla. In fact it was so thick that when kept in the refrigerator as required, it almost became a solid. I thought Max would love the taste of this stuff. Wrong! He hated it more than some of the really bad tasting stuff I've had to give him in the past. Dunno why. > I'm still really nervous about this but he says the worst it would do is > make her sick to her stomach in which case I would just stop giving it to > her. Does this sound right? Would she have to take it everyday. It's > awful how you read and read over and over about this stuff but until it's > happening to you it just seem to go in one ear and out the other. In both of my cases, I had to stop within two weeks due to the side effects. It was given every day at first, then every third day I believe after the first week. I wish you better luck with it than I've had. For the ferrets, Mike * Michael F. Janke - mjanke@gate.net * Member, South Florida Ferret Club & Rescue * * Shelter Home Page - http://www.gate.net/~mjanke 2.---------- Forwarded message ---------- Date: Wed, 20 Aug 97 11:13:37 PDT From: "Todd P. Cromwell III" Subject: need to make decision on initial approach w/Seldon (possibly to post) Feel free to post this to the adrenal list if you deem appropriate. What I was wondering is, Pam, if you have the time, briefly, what is the status of your sick pets and when did they have what surgeries done (so how long have they been able to hold up?)? I thought you said that Oreo was a bilateral adrenalectomy. Is she, and did you say something of growing adrenal tissue back or something, or other recurrent signs? Did you say you were treating Oreo with Lysodren, or was it one of your others? I need to make a decision and pursue a course of action with Seldon and his remaining adrenal gland. I am leaning toward trying this experimental drug therapy with Lupron that we discussed (apparently primarily for high estradiol). There has been a small amount of talk another approach, Ketoconisol (sp?) (apparently primarily for high testosterone). I am leaning away from lysodren because (a) in high enough doses to do good, reports of toxicity (b) possibility of going after the wrong cells and also perhaps exacerbating low blood sugar situation, (c) reports of it simply not working very well. I suppose there is the "pulsed dosage" possibility of which people talk. The surgery to remove his last adrenal is possible, but I might rather escalate and do that as a last resort, as I am quite scared of the zero-adrenal-ferret situation (how well have others maintained this and does it work in the end?), and, if the adrenals are stimulated somehow I might like to try to address that or interrupt a natural bad cycle rather than just removing yet another (and his only remaining) important adrenal gland, and the ultrasound showed the adrenal only perhaps slightly enlarged at this point - not totally haywire, though that could change quickly. On the other hand, surgery could look for insulinoma, though I'm still thinking there is a possibility that the malfunctioning adrenal could be contributing to the lack of blood sugar through bad management with whichever is relevant of glucocorticoids or minerocorticoids (esp. since the blood sugar is so constant at 50-60). On the plus side for surgery, Seldon is a good candidate now for surgery, not guaranteed in the future. Todd 3.---------- Forwarded message ---------- Date: Fri, 22 Aug 1997 11:49:17 -0400 (EDT) From: ShariDiane@aol.com Subject: Fwd: Adrenalectomy Lynn: You can include this FML & TriFL post to the Adrenal List. Keep us posted on Wally. Shari --------------------- Forwarded message: Subj: Adrenalectomy Date: 97-08-22 11:44:27 EDT From: ShariDiane To: ferret-list@cunyvm.cuny.edu CC: trifl@webslingerz.com Two weeks ago, I noticed minimal vulva swelling in my 3.9 yo female MF fuzzlove Gina. Last week, a pronounced swollen vulva with hairloss on the tip of her tail was observed. Monday, the vet confirmed my diagnosis ;-). Adrenal Gland Tumor. Surgery was Thursday. The tumor was on the right. In the "old" days (last year), a right gland tumor was considered inoperable. Dr. Bruce Williams, DVM reported in the FML Adrenal FAQ that this was no longer true - the vena cava in the right gland *could* be ligated (tied-off) and the tumor removed. (FYI-both glands can be removed.) Luckily for North Carolina ferrets, we have a vet that took the time to research and confer with Dr. Williams about this information, and has completed six (6) right Adrenal Gland Tumor surgeries this Spring/Summer. It is a 4 hour time consuming and technical operation. Dr. Dan Hudson of Northwoods AH in Cary, NC will be the Guest Speaker at the Oct. 18th meeting of the Triangle Ferret Lovers club. Topic: Adrenalectomy. He has offered to bring Gina's tumor for show and tell. Not sure if I can stomach that... Are you lurking and considering purchasing or adopting a ferret? Ask yourself if you can unexpectedly afforded an estimated $300 (left gland) or $500 (right gland) surgery. If you already have a carpet shark, start saving money - seriously. Do you have a ferret shelter in your area? Just think if they have several surgeries scheduled...Could you make a donation in care of their vet? If you haven't already done so, download the FML Disease FAQs and distribute to your area vets (TriFL members email me first). Thank you! to all that have inquired about Gina's health...your telephone calls and emails really helped. Shari Gunter Triangle Ferret Lovers club, North Carolina http://www.trifl.org